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Blood work results - question

Luxferro

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I agree female studies are flawed because crashed E2 is what I would consider a sadistic long term treatment plan for women as it sets off a set of health problems that are too long to list, just so they can technically survive breast cancer as their quality of life nose dives.

Women studies are obviously too extreme to use for anything other than an indictment against the cancer treatment industry that is obsessed with long term care for longer term profits.

As for men, of course you don't want high E2, it obviously isn't optimal for men and occasional use of moderate AI to control times when you know E2 is gonna elevate and cause side effects would be prudent.

And I'll agree DHT derivatives do come with risks and I have had those things happen to me.....poor lipids, prostate growth(getting up 3 times a night to go to the bathroom), elevated blood pressure, faster rise in hct.

I guess do what you have to do, Aromasin was my choice when I was using AI as it had the least known side effect profile. That said even lower doses for me made me feel like crap mentally, I felt flat in the gym, lost motivation. I find there are lots of ancillaries that I can't take without sides that I don't want to deal with.

For me it goes back to the more frequent doses to keep peaks low to prevent spill over that ends up as too high E2.
Yep! In your case it may have been that you were lowering your E2 too much with the AI. Every person’s sweet spot for E2 is different. What works for me may make you feel awful and vice versa
 

Luxferro

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I just wanted to add this as a general point for everyone here:

In breast cancer patients, the maximal E2 reduction observed with daily 25 mg of Aromasin was 62-65%. With anastrozole it was 80-85% and with letrozole it was 90-95%. Based on these data, I strongly believe that crashing your E2 with Aromasin would be very difficult.
 
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