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HGH injection timing

Donuts

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What’s the best protocol for 4iu a day?

I’ve been doing 2iu fasted, then I usually eat my first meal (high carbs) 30 mins after. Then I take my 2nd injection of 2iu right before bed (30-45 mins after my last meal). Does timing like this matter? Should I be waiting longer?
 

psauce

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No one knows when you eat first or go to bed, or what you're looking to get from the HGH.

If I was taking it, I would take it ~30 minutes before fasted cardio to obtain the best fat burning effect and at night to take advantage of the sleep quality improvement and tissue repair.
 

-WG-

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No one knows when you eat first or go to bed, or what you're looking to get from the HGH.

If I was taking it, I would take it ~30 minutes before fasted cardio to obtain the best fat burning effect and at night to take advantage of the sleep quality improvement and tissue repair.
This is good advice. The timing is a bit off as it takes a lot longer than 30 min to get into the meat of peak levels.. Which is why my advice would be as follows.. Just take it consistently, when it is the most convenient/works best for your situation. A lot of this stuff is really just splitting hairs, and not worth disrupting your life for..

If goal is fat loss, and you can easily do it a few hours before fasted cardio, then do that..
Priority is muscle gain/recovery, and you can take it pre-bed, try that.

But If you have to cut sleep short/disrupt sleep to do it before fasted cardio, then probably not worth it...
Some people get tired as fuck if they take it in the morning.... Try it at night.
Some people can't sleep taking it at night.. Try in the morning...

Just get it in :)
 

Lee_48157

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I agree w the fact that 30 mins prior to fasted is not nearly enough time. Dr Dean St Mart just had something about this on his IG today. One popular coach I listen to says he has his clients leave out a loaded pin of GH in their bathroom before they go to bed, and when you get up naturally to pee in the middle of the night that’s when they do it… then wake up & do your fasted cardio for fat loss.

I know some might say they don’t always wake up or not at the same time, but if all your variables are the same day to day at least for myself I wake up and pee about the same time at night.

For most that might be doing too much, but it’s an example. Other than that pre training can be useful for lagging muscles to feel them because he gets a great pump and connects with the muscle better (Andrew berry uses this technique) , some do it post workout, and many do it pre bed.
 

-WG-

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Yea just be cognizant of the fact a lot of this is just made up. Things like "I take it prewo because I connect with the muscle better" Ok maybe you think that is happening, which is completely fine because even placebo can be helpful... But if taking GH IM/SUB Q 30 min pre-wo very little is happening. lol
 

Lee_48157

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Yea just be cognizant of the fact a lot of this is just made up. Things like "I take it prewo because I connect with the muscle better" Ok maybe you think that is happening, which is completely fine because even placebo can be helpful... But if taking GH IM/SUB Q 30 min pre-wo very little is happening. lol
Exactly I agree, he was asking so I was just trying to give some examples of some of the protocols I’ve heard over the years. You’d have to do IV if you wanted it to work that quickly. Idk anyone that’s doing that lol
 

psauce

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The timing of GH administration has to do with when the serum level peaks and what you want it for. From IM injection to serum peak is about 2 hours. If you want the lipolytic effect, it is ideal to time your administration to coincide with increased metabolic activity. Since serum free fatty acid values spike during exercise and drop (but remain elevated) for about 3-6 hours, injecting shortly before activity is ideal.

The reason I don't agree with the advice to inject substantially before is because, since GH stimulates lipolysis, you want to avoid maximum GH serum levels when 1) you're inactive, because the FFAs will just go back into adipose tissue, or 2) when lipolysis is already spiked, and the rate-limiting step is transport to the mitochondria.

If you inject a little bit before fasted cardio, you'll get the cardio peak of FFAs, it will attenuate, then the GH-induced lipolysis will kick in.

There's nothing voodoo about any of it.
 

-WG-

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Peaks in roughly 2hrs and remains elevated for hours after. So for me "ideal" would be more time than 30 min personally.

But point is, it doesn't matter, and is splitting hairs. If one is easier, and causes less disruption, then do that. People love to get buried in the minutia, and often times just make things more complicated than it needs to be.

Over the the last decade, I have ran every single possible protocol imaginable, and in the end, it is all very similar in terms of results.
 

FrancoC

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What about the timing to minimize insulin resistance? I’ve seen where it’s best to take it no sooner than 90min after your last meal before bed to prevent that
 

-WG-

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What about the timing to minimize insulin resistance? I’ve seen where it’s best to take it no sooner than 90min after your last meal before bed to prevent that
Let me ask this. How much GH are you planning on running?
 

-WG-

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Let’s say 2-4iu, all dosed at one time
So a few things to unpack.

1. Research seems to show that it isn't GH directly that causes insulin resistance it is an abundance of FFA's released and not dealt with. Hence why obese people tend to have shit insulin sensitivity and are insulin resistant. So pre bed probably not ideal in that regard. Like Psauce mentioned above pre fasted cardio, or at least exercise is preferable in terms of FFA utilization.

2. Studies also have shown that low dose GH ie. < 0.01mg/kg per day has little effect on insulin sensitivity/resistance. It is more an issue with higher doses. Like keep in mind HIV patients are generally prescribed 18iu of Serostim a day.... That is A LOT lol

And that said, taking metformin or berberine can help in this regard, and something I personally do anyway.
 

Bilge

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What’s the best protocol for 4iu a day?

I’ve been doing 2iu fasted, then I usually eat my first meal (high carbs) 30 mins after. Then I take my 2nd injection of 2iu right before bed (30-45 mins after my last meal). Does timing like this matter? Should I be waiting longer?
I am currently running 4iu/day. Pin 2iu pre workout. 2iu before bed. I like this better than all 4iu at once.
 

parksisme

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I dont want to split hairs, just want to be optimal. I wake up at 430am to get ready for work eat around 5am, I leave for work 530am. I go to bed at 830pm. I usually train 430pm. Ideally it would be wake up at 415am, take a dose, go to gym and do 30 minutes of cardio and then go to work and eat around 7am.
I dont want to over complicate it reading a lot and seeing lots of different approaches.
 
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