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I'm on TRT and fat. Once gyno is detected how quick do you have to act? Can I wait for bloods at week 6?

BrodTT

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I’m on 160mg of test cyp a week - divided into two doses and am on week 5 of this regimen. I’m fat (35 years old, 6’5 and 275 lbs, linebacker build but not cut up - got a 41 inch waist) and have been religiously checking myself for gyno. I haven’t had sore/spicey nipples at all but I still check to be sure. Tonight I felt a small lump when I push directly down on my left nipple (and slightly to the right of it, not underneath it) about the size of a pea - but I can’t feel it when I “cup and feel” like the Youtube videos are saying to test for. I can sort of feel it when I flex my pec, it maybe brings it up from the surface so to speak.

So, I have two questions:

- I have 30 ct 1mg Arimidex that the TRT clinic prescribed me, but I’ve heard a lot of horror stories of guys getting shut down and I don’t want to run the risk of taking it if I don’t need it and I’m just feeling something else. Would taking half a pill a week kill my E2?

- I have my first blood test about 4 days from now since starting TRT, should I be able to wait until then to see what my E2 levels are? Or is this an “act immediately” situation? Haven’t run into this before.

I know I'm going to catch shit for getting on any kind of test when I'm a fatty but IDGAF. In the past 18 month depression I've had my sister die to a drunk driver, lost my job, had oneitis marry my high school bully and rear his kid, etc. boo hoo blah blah tl;dr I've had a shitty time since 2021 and gained 60 lbs of fat. I was cut up before 2021 @ 220. I've been so miserably depressed and lacking in energy, confidence, drive, etc. that being on TRT I've felt the veil lift for the first time in literal fucking years and I've actually gone back to the gym & lost 10 lbs since starting this in March.

My last test results (before I hopped on) are:

Total T = 359
Test Free = 67.3 (ref 47-244)
SHBG = 23
Prolactin = 9.1
FSH = 2.8
PSA total= 1.11
Estradiol = 17.3
DHEA = 5.5

Thanks guys, I appreciate the help.
 

psauce

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Having too much* fat causes hypogonadism, and you’re taking a hormone replacement dose to correct your health. If anyone gives you shit for that, tell them to fuck off.

Wait for the blood test. You’ll ruin the validity of the measurements if you take anything new right now… you won’t know if you had high estrogen, or if this was just a bruise from all the self-tit-poking you’re doing.
 
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BrodTT

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Having too fat weight causes hypogonadism, and you’re taking a hormone replacement dose to correct your health. If anyone gives you shit for that, tell them to fuck off.

Wait for the blood test. You’ll ruin the validity of the measurements if you take anything new right now… you won’t know if you had high estrogen, or if this was just a bruise from all the self-tit-poking you’re doing.

So hypothetically if my E2 is high and this is gyno, are the odds still in my favor for being able to reverse it even if its been around for a few weeks?
 

psauce

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I wouldn’t wait several weeks, but a few days isn’t going to kill you.
 

Scaryclownz

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Raloxifene has always been my go to for mild gyno reversal. When I was still fairly new to this, I developed a slight case of gyno (although I didn't know this initially as, for my body, gyno tissue seems to develop more in the outer area of my chest lateral to my nipples - not directly under/behind nips, - weird I know). But once I realized a small lump had developed and confirmed estrogen was elevated with bloodwork - Raloxifene and better estrogen management has completely reversed the course. Scary at first and not something you want to take lightly, but labs are essential. As you gain experience with learning this game, it becomes much easier to recognize your body and respond accordingly - Don't panic, get lab work, and always keep some ancillaries on hand before you start a cycle.
 

Gbunk

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Sorry to hear about the rough time, life can be brutal. That’s great you are feeling better. These guys nailed it on the head. My go to is raloxifene if I start getting a lump.
 

BrodTT

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Having too much* fat causes hypogonadism, and you’re taking a hormone replacement dose to correct your health. If anyone gives you shit for that, tell them to fuck off.

Wait for the blood test. You’ll ruin the validity of the measurements if you take anything new right now… you won’t know if you had high estrogen, or if this was just a bruise from all the self-tit-poking you’re doing.


Estrogen came back at 44, Testosterone is at around 750. Should I take an AI or just hold off? Not really feeling any sides at this point, no itchy/tender nips or anything. Only symptom I'm seeing is that I can be slightly more emotional/sentimental around 24 hours after injection.
 
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Arimidex makes me feel like shit sometimes but that's depending on where my e2 is at. I don't get labs weekly of course so I just base it off a couple things.

1. Mood. When I am feeling extra touchy and anxious which is usually every 6 days or so when I am running higher than 200mg.

2. I'll notice I'll be beating my D like it owes me money and it'll start getting somewhat soft and hard to finish and same for sex. When everything's in check hard as a rock and consistent.

Half a tablet a week highly doubt will tank your estrogen. E2 is more than just sensitive nipples. When you get those other side effects it may be something you need to address so you feel better. I was actually feeling quite anxious yesterday and just off, cloudy etc and took half a tab and today feel great. Just be careful it's kind of a shitty med and will mess you up if you take too much.
 

coupastar

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didn't read any comments , but if you are on trt just call the doc and get something asap! be safe
 

psauce

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Estrogen came back at 44, Testosterone is at around 750. Should I take an AI or just hold off? Not really feeling any sides at this point, no itchy/tender nips or anything. Only symptom I'm seeing is that I can be slightly more emotional/sentimental around 24 hours after injection.
Just my opinion, but that is barely outside of the reference range and I wouldn’t touch it.

If you decide you want to do something about it, calcium glucarate is a lot more mild than the AIs out there. I would start with a tiny dose of that as my first approach to bringing E2 down a little bit.

I know I’m a broken record, but if you’re doing hormone replacement, treat symptoms, not blood numbers. Unless you feel bad, more compounds only means more potential problems.
 

Scaryclownz

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Just my opinion, but that is barely outside of the reference range and I wouldn’t touch it.

If you decide you want to do something about it, calcium glucarate is a lot more mild than the AIs out there. I would start with a tiny dose of that as my first approach to bringing E2 down a little bit.

I know I’m a broken record, but if you’re doing hormone replacement, treat symptoms, not blood numbers. Unless you feel bad, more compounds only means more potential problems.
I agree with psauce. Have you checked your prolactin levels as well? When you mentioned going limp, it made me wonder about possible Prolactin issues. E2 seems normal, but there may be other variables at play (which is why I'm such a strong advocate of having comprehensive lab work done consistently) - it's about the endocrine SYSTEM and all parts play a role. Just tryin' to help bro.
 

BrodTT

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Just my opinion, but that is barely outside of the reference range and I wouldn’t touch it.

If you decide you want to do something about it, calcium glucarate is a lot more mild than the AIs out there. I would start with a tiny dose of that as my first approach to bringing E2 down a little bit.

I know I’m a broken record, but if you’re doing hormone replacement, treat symptoms, not blood numbers. Unless you feel bad, more compounds only means more potential problems.
I agree with psauce. Have you checked your prolactin levels as well? When you mentioned going limp, it made me wonder about possible Prolactin issues. E2 seems normal, but there may be other variables at play (which is why I'm such a strong advocate of having comprehensive lab work done consistently) - it's about the endocrine SYSTEM and all parts play a role. Just tryin' to help bro.

Got it, I think I'll leave it alone. Actually whatever swelling/puffiness that was there in week 2-3 has pretty much all vanished at this point. No issues with my erections either, they seem to be at 110-120% of what they were before TRT now. Seems like it took me about 8 weeks for my body to adjust to this dose and figure itself out. I'm only at 750-ish total T so twice my natty level and I feel much better, more content, more motivated, more energy, etc. Don't see a reason to mess with it too much at this point.

Thanks for the help guys (have also lost about 6 more lbs since the beginning of May, but that's more diet/time at the gym).
 

BrodTT

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I want to just bump this topic 5 months later and say that I'm now 235lbs and have a 35 inch waist, and if I have had any gyno during the initial stages (couldn't really tell) it definitely wasn't permanent. What's crazier is that at 280 I was able to bench 315 for 2-3 reps but 45lbs lighter I can still do a clean rep of 295, could probably even do 305/315 again on a day when I'm in the zone.

It's absolutely insane how much TRT has preserved my muscle while I've been on a strict deficit. I'm glad I made the decision to do this and a sincere thank you to the support from the community here. Definitely been feeling like I've gotten my life back under control after that horrendous year.
 
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joneshill

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Act right away. mine literally developed within a few days after i felt the pain
 

AlexDavis43

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I see there's some pushback against getting the glands removed. It's an easy low risk surgery.

As long as it's an actual surgeon and you're not trying to get a discount by using an underground back alley surgeon with rusty instruments, should be gtg
 

300

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Glad to hear the positive experience TRT has provided, 1 thing I would like to point out is if you are worried about gyno please up the administration frequency so you have less variation in aromatization, as well as try to lose fat since the aromatase enzyme is expressed heavily in fat tissue, I understand this takes time. As far as gyno is concerned once it's there it's there. It's like asking how long do I have to act if I have a heart attack, well you can't stop yourself from having had the heart attack but you can go to the ER to prevent it from killing you (or in the case of gyno growing larger).
 
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