SLU-PP-332

[Sector]

Let’s get one of these going for SLU, a compound that very much intrigues me

Post your experiences with the compound listed in the title here. Anything from doses, length of time ran, sides, gains made, gains kept, bloodwork changes, and any other positives or negatives with the compound

 

[Sector]

AI data dump on the compound:

• SLU-PP-332 is a potent, selective PPARδ (PPAR-beta/delta) agonist.
• Similar in mechanism to GW501516 (Cardarine) but with potentially different pharmacokinetics.
• PPARδ activation upregulates genes responsible for fatty acid oxidation, mitochondrial biogenesis, and glucose utilization, enhancing endurance and fat utilization.

Potential Benefits

Fat Loss:

• Increases fatty acid oxidation in skeletal muscle and liver.
• Spares glucose while using fat for fuel, promoting body fat reduction, especially under a calorie deficit.
• May reduce triglycerides and improve lipid profiles.

Endurance Enhancement:

• Increases mitochondrial density and oxidative fibers in muscle.
• Allows greater endurance with less perceived effort, beneficial for cutting phases with cardio.

Glucose Utilization & Insulin Sensitivity:

• May improve insulin sensitivity, aiding recomposition.
• Helps stabilize blood glucose while dieting.

Muscle Preservation During Cuts:

• By shifting the body to fat utilization, it may help preserve lean tissue during caloric restriction.

Potential Cognitive Benefits:

• Some PPARδ agonists may reduce neuroinflammation and improve cognitive resilience, although data on SLU-PP-332 specifically in humans is lacking.

Potential Hepatoprotective Effects:

• Some evidence PPARδ agonists reduce liver fat and fibrosis markers.

 

[workout1234]

Following. I've also been curious about SLU for my next cut.

 

[Geardad]

I played with it for a few weeks. Morning cardio was notably easier, other than that, I didn’t notice much, but I’d have to run it for a few months to determine if there were any other noticeable effects. I was using 1000mcg 30 minutes pre-cardio. I’m curious to know others experiences as well.

 

[workout1234]

When you say cardio was easier, do you mean perceived effort or you felt you had more endurance? I'm trying to mentally understand if SLU is relatable to other compounds like l-carnitine injections for enhancing cardio via endurance or if the effects are different and more like how you feel strength-wise when on AAS and things just "feel easier" (but the cardio equivalent).

 

[Geardad]

I guess I would say more endurance. I don’t feel as gassed at the end of a cardio session, and the “calories burned” on my elliptical was significantly higher during the same elapsed time that I always do. Could be placebo I guess, but I don’t think it was.

 

[Catteni]

Let’s get one of these going for SLU, a compound that very much intrigues me

Post your experiences with the compound listed in the title here. Anything from doses, length of time ran, sides, gains made, gains kept, bloodwork changes, and any other positives or negatives with the compound

Almost picked some up, been eyeing it from a vendor just go the wife some Tirz from. Curious about it as well.

 

[snigglefutz]

I have been on 750-1000mcg daily, divided dose. It's been about 10 days, honestly, the only thing I really notice is increased sweating during lifts and cardio. Possibly some improved
blood sugar control / insulin sensitivity via the CGM i wear. I'm going to run it for 3-6 months before making any real judgements.

I'm mostly interested in the background metabolic support, more than weight loss.
Thinking of adding some MOTS-c to the mix in the coming weeks.

 

[Catteni]

Mine lands from Skye tomorrow or Monday via Fedex. 250mcg capsules.

Is 500mcg enough?

Ordered some MOTS-c too.

 

[Sector]

I’m going to try SLU soon too. Should be interesting . Prob will start with 250mcg fasted first thing am and post workout since I train in the morning

Kind of doing a slow bulk/recomp right now. Hoping I can keep pushing the weight up and even lean down more with HIIT cardio, a mild surplus and some help from compounds like hgh, SLU, l carnitine, and yohimbine on rest days with fasted cardio

 

[Catteni]

I’m going to try SLU soon too. Should be interesting . Prob will start with 250mcg fasted first thing am and post workout since I train in the morning

Kind of doing a slow bulk/recomp right now. Hoping I can keep pushing the weight up and even lean out about with HIIT cardio, a mild surplus and some help from compounds like hgh, SLU, l carnitine, and yohimbine on rest days with fasted cardio

View attachment 7851

Looking shredded man.

 

[Ryeguy]

I've used it on and off for a few months with doses ranging from 250mcg to 750mcg. The only thing I've noticed is it causes me to sweat a lot more when I work out. I don't doubt it has other effects, but I haven't perceived them.

 

[Ateam2024]

i ran up to 80 mg daily, 40 mg in morning, 40 mg mid afternoon, i noticed a rhr increase of 5-10 points, increased cardio output, more sweat, and i ran this for 4-5 months and now have lowered my daily dose down to 20 mg daily, rhr has reduced a few points , im sure from the reduction in dose, other than that it was kind of a lack luster compound, not to exciting imo,,

 

[Ateam2024]

I’m going to try SLU soon too. Should be interesting . Prob will start with 250mcg fasted first thing am and post workout since I train in the morning

Kind of doing a slow bulk/recomp right now. Hoping I can keep pushing the weight up and even lean down more with HIIT cardio, a mild surplus and some help from compounds like hgh, SLU, l carnitine, and yohimbine on rest days with fasted cardio

View attachment 7851

whats up fat boy!,jk looking good Brother,,

 

[Sector]

Slu just came in today, just dosed 250mcg

Will do 250mcg fasted and 250mcg post workout to start. Definitely interested to see what the hype is about, some people report it being amazing, some report feeling nothing from it, so I’m curious to see what happens

 

[workout1234]

Slu just came in today, just dosed 250mcg

Will do 250mcg fasted and 250mcg post workout to start. Definitely interested to see what the hype is about, some people report it being amazing, some report feeling nothing from it, so I’m curious to see what happens

Let's go! Curious to see how it treats you, ive been eyeing

 

[Sector]

Let's go! Curious to see how it treats you, ive been eyeing

Not sure if the effects are immediate, or takes time to ramp up in the system, but I’ll definitely let you know what I notice (if anything)

 

[Ateam2024]

Slu just came in today, just dosed 250mcg

Will do 250mcg fasted and 250mcg post workout to start. Definitely interested to see what the hype is about, some people report it being amazing, some report feeling nothing from it, so I’m curious to see what happens

let us know what that dose does? It seems so minuscule, but then again so many different doses and such its hard to say what will work for some and others? Take note of rhr as one variable as you probably already know, but that was one major thing i noticed when mega dosing it, since ihave pretty much dropped using the Slupp, my rhr is back to 64, and i have noticed a little less vascular, but that could just be because i been eating like a tird lately aha,

 

[Gonz0]

AI data dump on the compound:

• SLU-PP-332 is a potent, selective PPARδ (PPAR-beta/delta) agonist.
• Similar in mechanism to GW501516 (Cardarine) but with potentially different pharmacokinetics.
• PPARδ activation upregulates genes responsible for fatty acid oxidation, mitochondrial biogenesis, and glucose utilization, enhancing endurance and fat utilization.

Potential Benefits

Fat Loss:

• Increases fatty acid oxidation in skeletal muscle and liver.
• Spares glucose while using fat for fuel, promoting body fat reduction, especially under a calorie deficit.
• May reduce triglycerides and improve lipid profiles.

Endurance Enhancement:

• Increases mitochondrial density and oxidative fibers in muscle.
• Allows greater endurance with less perceived effort, beneficial for cutting phases with cardio.

Glucose Utilization & Insulin Sensitivity:

• May improve insulin sensitivity, aiding recomposition.
• Helps stabilize blood glucose while dieting.

Muscle Preservation During Cuts:

• By shifting the body to fat utilization, it may help preserve lean tissue during caloric restriction.

Potential Cognitive Benefits:

• Some PPARδ agonists may reduce neuroinflammation and improve cognitive resilience, although data on SLU-PP-332 specifically in humans is lacking.

Potential Hepatoprotective Effects:

• Some evidence PPARδ agonists reduce liver fat and fibrosis markers.

I’ve been using Slu for roughly 1 year at doses ranging from 1mg - 5mg. I get a sense of well being and an increase of energy roughly an hour after taking it. Keeps me hotter throughout the day and I want to say it kept me leaner during my mass phase but it’s hard to tell if it was the Slu or everything else I was running. I’ll be trying the injectable version soon.

 

[Sector]

I’ve been using Slu for roughly 1 year at doses ranging from 1mg - 5mg. I get a sense of well being and an increase of energy roughly an hour after taking it. Keeps me hotter throughout the day and I want to say it kept me leaner during my mass phase but it’s hard to tell if it was the Slu or everything else I was running. I’ll be trying the injectable version soon.

Definitely appreciate the review. I’m hoping to see some good things from it, all my other variables are about as consistent as I can get them so I’m hoping it’ll help me lean down more or at worst, get an endurance boost for my workouts

let us know what that dose does? It seems so minuscule, but then again so many different doses and such its hard to say what will work for some and others? Take note of rhr as one variable as you probably already know, but that was one major thing i noticed when mega dosing it, since ihave pretty much dropped using the Slupp, my rhr is back to 64, and i have noticed a little less vascular, but that could just be because i been eating like a tird lately aha,

Definitely will. I have Reta kind of skewing my rhr at the moment but if I notice it going up more from the slu I’ll have to make some adjustments.

And yeah I see the dosages all over the place. Seen IFBB pros raving over it at 250-500mcg a day, then see some people running 20-100mg. Dosages are all over. I figure it’s probably best to start at the low end, try to get a feel for it, see if anything’s happening, then I can always increase it later rather than jumping into the deep end too soon. Realistically I’ll probably bump in to 500mcg am and 500mcg post workout in a few weeks if I’m seeing nothing at all. Probably won’t go higher than that. And if it’s working at 250/250 I’ll probably just leave it there