Blood work test results

[ben76]

Hey yall!

So I've been currently running trt sense 2020 I had gotten my blood work done backing 2020 and my test was sitting at 320. I was super sluggish tired and just a fat piece of shit and I was only 30 years old! So i decided i needed to make changes. And now I'm 14 weeks out from my 1st bodybuilding show.
So i had came across this fourm through a friend to better deals on my "vitamins" I currently got sus250 and arimidex from Azteca gold. And these are my results after 6 weeks of running 300mg/l a week. High quality stuff!

 

[Deucalion]

Bruh that HDL... and your potassium along with kidney function.... ALT.... Do you take creatine supplements? How old r u?

 

[ben76]

Yea ive always had a low hdl even when I wasn't running trt. I do take 5mg of creatine hcl a day, along with multivitamin, krill oil, vitamin c, apple cider vinegar capsules, 5htp, milkthistle, p5p, kidney cleanse and drink 2gal of water a day. I'm 33

 

[Deucalion]

I mean your labs are impressive for what you are taking but respectfully at 33 these other labs are not good bro. You NEED to fix your cholesterol, your cardiac risk must be insane. I am a little jaded, I understand on testosterone <HDL >LDL is common but I think you need to start taking steps to mitigate risk...

PERSONALLY, I would stop creatine, because your potassium is rising and your blood osmolarity looks about the same, so dehydration does not look too likely as the cause for such a high increase. I would start taking soluble fiber asap to lower LDL short term while you make dietary changes to incorporate in more healthy fats to raise HDL long term. HIGHLY consider a -statin medication! Switch out milk thistle with TUDCA. Also, idk what is happening with your alk phos could be low zinc, low mag, etc. What is your multivitamin looking like?
Then of course get re-tested... CMP's usually cost $20-30$

You have to be careful with TUDCA though it can lower blood sugar by increasing insulin sensitivity.

 

[achba]

Hey yall!

So I've been currently running trt sense 2020 I had gotten my blood work done backing 2020 and my test was sitting at 320. I was super sluggish tired and just a fat piece of shit and I was only 30 years old! So i decided i needed to make changes. And now I'm 14 weeks out from my 1st bodybuilding show.
So i had came across this fourm through a friend to better deals on my "vitamins" I currently got sus250 and arimidex from Azteca gold. And these are my results after 6 weeks of running 300mg/l a week. High quality stuff!

You need to get that potassium down, restrict any high potassium foods until you know the cause. Any BP meds (may end in -pril or -sartan) diuretics, blood thinners? Those can raise potassium. High potassium messes with your heart, your levels arent an emergency but you need to get checked out or have meds reevaluated.

Your cholesterol is fine btw, HDL is not important and your LDL is fine. If you look at all the medications that raised your HDL like niacin youll see that they are no longer prescribed because they do not improve cardiovascular outcomes. Compare that with medications that lower LDL and you see excellent reductions in mortality. LDL just needs to stay under 93 according to the MESA guidelines.

Your creatinine suggests there is something wrong with your kidneys, and hyperkalemia or high potassium is often a finding with impaired kidney function. See a doctor asap.

This is the wrong place to post bloods btw.

 

[Deucalion]

You need to get that potassium down, restrict any high potassium foods until you know the cause. Any BP meds (may end in -pril or -sartan) diuretics, blood thinners? Those can raise potassium. High potassium messes with your heart, your levels arent an emergency but you need to get checked out or have meds reevaluated.

Your cholesterol is fine btw, HDL is not important and your LDL is fine. If you look at all the medications that raised your HDL like niacin youll see that they are no longer prescribed because they do not improve cardiovascular outcomes. Compare that with medications that lower LDL and you see excellent reductions in mortality. LDL just needs to stay under 93 according to the MESA guidelines.

Your creatinine suggests there is something wrong with your kidneys, and hyperkalemia or high potassium is often a finding with impaired kidney function. See a doctor asap.

This is the wrong place to post bloods btw.

Agree with some of what you said, but HDL is very important. Niacin was found to increase HDL-C which had no cardiovascular improvement. Where as HDL-P and ApoA-I did improve CV risk. The fact his LDL jumped up and HDL dropped puts him at a higher CV risk alone. The ratio of HDL and LDL is important. MESA saying keep your LDL under 93 is like saying why do steroids if you are already fit? Decreasing your LDL and increasing HDL more will impact your CV health. Just like adding steroids will help a fit person improve their physique further.

only diuretics like aldactone spare potassium, loops and thiazides will wash potassium out along with other electrolytes.

 

[Deucalion]

@ben76 - I am mildly invested what are your plans to rectify these labs? you can't continue on the path you are going man that potassium is not good. You are too young for all that, I do not really see any thing that pops out at me that you are taking that would cause these issues. You are not taking any other medications?

Maybe consider a Cystatin C blood test to measure how your kidneys are really functioning... $40 on ulta labs

 

[achba]

Agree with some of what you said, but HDL is very important. Niacin was found to increase HDL-C which had no cardiovascular improvement. Where as HDL-P and ApoA-I did improve CV risk. The fact his LDL jumped up and HDL dropped puts him at a higher CV risk alone. The ratio of HDL and LDL is important. MESA saying keep your LDL under 93 is like saying why do steroids if you are already fit? Decreasing your LDL and increasing HDL more will impact your CV health. Just like adding steroids will help a fit person improve their physique further.

only diuretics like aldactone spare potassium, loops and thiazides will wash potassium out along with other electrolytes.

Regardless if HDL:LDL ratio is important theres no way to specifically raise the smaller HDL particles with medication, which are considered the healthy ones.Statins are proven to reduce mortality by lowering LDL. If you look at people with familial hypobetalipoproteinemia who have reduced LDL and normal or slightly elevated HDL they have much lower morbitity and mortality and live longer than people with typical LDL cholesterol.

 

[Deucalion]

Regardless if HDL:LDL ratio is important theres no way to specifically raise the smaller HDL particles with medication, which are considered the healthy ones.Statins are proven to reduce mortality by lowering LDL. If you look at people with familial hypobetalipoproteinemia who have reduced LDL and normal or slightly elevated HDL they have much lower morbitity and mortality and live longer than people with typical LDL cholesterol.

Fatty acids can improve ApoA-I and HDL. I agree, statins do raise HDL but I am unsure if it is effective I read they don't think it is, I know the real effects are the reduction in LDL when it comes to medication. The thing is though, the more HDL the less LDL you should have since HDL transports LDL for metabolism/excretion. That is why I recommended soluble fibers and statins to reduce LDL, until dietary change can occur to bring up their HDL.

Subjectively, time and time again the individuals I have seen that need multi-vessel cabgs are people who have seriously low HDL <20 like this individual. They even had "normal" LDL levels well under the MESA guidleines of 93. Something about normal LDL and low HDL is a recipe to atherosclerosis.

I think with everything that is going on with this individual cardiac, kidney, and possibly liver related consideration regarding optimizing their cholesterol should be on the table for them....

 

[ben76]

@ben76 - I am mildly invested what are your plans to rectify these labs? you can't continue on the path you are going man that potassium is not good. You are too young for all that, I do not really see any thing that pops out at me that you are taking that would cause these issues. You are not taking any other medications?

Maybe consider a Cystatin C blood test to measure how your kidneys are really functioning... $40 on ulta labs

I don't currently take any meds prescribed by a Dr, i dont drink just smoke weed. But all I take for supplements is what I had posted before oh and I drink a fiberlyze every night before bed. I don't eat shitty/greasy foods im on a meal plan with a coach. And of course a magority of it is lean ground elk/deer, green beans, rice chicken, egg whites, English muffins. And if I do get a re feed meal is useally sushi or a burger

 

[achba]

Fatty acids can improve ApoA-I and HDL. I agree, statins do raise HDL but I am unsure if it is effective I read they don't think it is, I know the real effects are the reduction in LDL when it comes to medication. The thing is though, the more HDL the less LDL you should have since HDL transports LDL for metabolism/excretion. That is why I recommended soluble fibers and statins to reduce LDL, until dietary change can occur to bring up their HDL.

Subjectively, time and time again the individuals I have seen that need multi-vessel cabgs are people who have seriously low HDL <20 like this individual. They even had "normal" LDL levels well under the MESA guidleines of 93. Something about normal LDL and low HDL is a recipe to atherosclerosis.

I think with everything that is going on with this individual cardiac, kidney, and possibly liver related consideration regarding optimizing their cholesterol should be on the table for them....

In high risk patients you'd want LDL down to 55 or less, there have also been some trials where they obliterated LDL with a statin+pcsk9 inhibitor to 10-25 and they saw continued reductions in ascvd events, especially in patients with prior mi or mvcad.

 

[Deucalion]

I don't currently take any meds prescribed by a Dr, i dont drink just smoke weed. But all I take for supplements is what I had posted before oh and I drink a fiberlyze every night before bed. I don't eat shitty/greasy foods im on a meal plan with a coach. And of course a magority of it is lean ground elk/deer, green beans, rice chicken, egg whites, English muffins. And if I do get a re feed meal is useally sushi or a burger

There is nothing in your diet/supplement stack that should be raising your potassium like that. There is a small chance the blood partially hemolyzed but I doubt it since your last result was boarder-line high.

Do your lab results concern you? Were you taking creatine back in january?

 

[Deucalion]

In high risk patients you'd want LDL down to 55 or less, there have also been some trials where they obliterated LDL with a statin+pcsk9 inhibitor to 10-25 and they saw continued reductions in ascvd events, especially in patients with prior mi or mvcad.

I think this man is high risk... He is on his way to kidney disease, liver disease, and heart disease and he is only 33 years old...

Damn, I wonder how someone would feel with an LDL of 10-25. Possibly pretty shitty I would imagine, I think at that point I will take the 0.01% higher risk of cardiac events haha...

 

[achba]

I think this man is high risk... He is on his way to kidney disease, liver disease, and heart disease and he is only 33 years old...

Damn, I wonder how someone would feel with an LDL of 10-25. Possibly pretty shitty I would imagine, I think at that point I will take the 0.01% higher risk of cardiac events haha...

Its a 20% risk reduction or more and also 15% reductions in all cause mortality. There wasnt any issues with the patients in terms of serious side effects, including cognitive ones other than drug related side effects which were mild. Cholesterol does not penetrate the BBB and the brain makes it own.

 

[Deucalion]

Its a 20% risk reduction or more and also 15% reductions in all cause mortality. There wasnt any issues with the patients in terms of serious side effects, including cognitive ones other than drug related side effects which were mild. Cholesterol does not penetrate the BBB and the brain makes it own.

20% reduction of risk from an LDL of what to what? What was the length of time for this study that there were no serious side effects?

 

[achba]

20% reduction of risk from an LDL of what to what? What was the length of time for this study that there were no serious side effects?

Safety and Efficacy of Extremely Low LDL-Cholesterol Levels and Its Prospects in Hyperlipidemia Management

The risk of cardiovascular disease has been reported to have a linear relationship with LDL levels. Additionally, the currently recommended LDL target goal of 70 mg/dl does not diminish the CV risk entirely leaving behind some residual risk. Previous ...

www.ncbi.nlm.nih.gov

A lot of these studies went on for months to years and included tens of thousands of patients.

 

[Deucalion]

Safety and Efficacy of Extremely Low LDL-Cholesterol Levels and Its Prospects in Hyperlipidemia Management

The risk of cardiovascular disease has been reported to have a linear relationship with LDL levels. Additionally, the currently recommended LDL target goal of 70 mg/dl does not diminish the CV risk entirely leaving behind some residual risk. Previous ...

www.ncbi.nlm.nih.gov

A lot of these studies went on for months to years and included tens of thousands of patients.

Interesting read, psck9 inhibitors do have common side effects like fatigue. The study was cool, I guess we are seeing the power of monoclonal antibodies. Although, it only cited information for individuals who were born with the psck9 mutation not taking the inhibitor from what I could read in regards to not having side effects.