Enhanced Cruise

[ragemedic]

What is up fellas. Wondering what you guys do for “enhanced cruising”. I normally Blast for 12-16 weeks once a year and then come down to 180mgs to 200mgs of just test the rest of the year. I have found adding primo during my cruise at the same level as my test has helped me further some gains without impacting blood markers. Wondering if anyone else does something similar with other compounds. Recently read a thread of people swearing by adding MENT to a cruise to enhance it.

 

[chimpanzee19]

This is just a blast.

The point of cruising is to down regulate your androgen receptors so you can blast and still keep getting gains every time.

Cruise should be at like ~120mgs/week max

 

[system]

@chimpanzee19

You not worried about health? Most cruise to get your bloods back in order… not everything can be controlled

 

[chimpanzee19]

@nswole1 The reason for cruising is also for health. It’s multi-faceted and, despite bloodwork being in the clear, there’s more than one reason to cruise. The “enhanced” cruise outlined is not a cruise.

 

[chimpanzee19]

@nswole1 Not 100% why you tagged me to inquire about health. OP is justifying the “enhanced” cruise by saying bloods look ok. I’m only pointing out that this is not a cruise.

 

[Forthewin1123]

@chimpanzee19 I agree with giving the receptors a break and getting bloods in check… bit to say 120mgs a week max is not true… he said enhanced cruise… also there’s lots of guys who need 150-200mg a week to be high normal test… 700-1000ng/dl… also if this guy or any guy has a lot of muscle beyond his natural limit… going to 120mg he could lose alot of muscle.

My opinion is that there is general definition of a cruise but depending on fje persona and their goals the cruise will vary…

 

[Jay]

AR RECEPTORS DONT DOWNREGULATE. The amount of times I hear this is maddening.

What happens is your myostatin levels elevate as time progresses on a blast and caps out at about 16-20 weeks. Thus why the plateau happens .

Health concerns aside. All an enhanced cruise would do is keep your myostatin at a constant peak rendering your next blast useless.

 

[chimpanzee19]

@Jay There’s many studies to support receptor down regulation and typically showing a 6 week turn around time. If anything, the majority of people who cycle year round, like the OP, have issues gaining size/are not very big in general. I would assume OP is not very big cycling year round essentially.

 

[chimpanzee19]

@Forthewin1123 Many I know take 120-150mgs with no issue and for the most part hold above 250lbs lean, only losing ~10lbs or so from what I assume is water retention or the ability to digest more efficiently. It takes some time to lose mass and it would disappear over time, however after 6 weeks off, things still seems to hold. In the end, a lot of this is individual and you have to do what’s best for you. Injecting testosterone, even at a lower dose than a normal range for men, is going to be far above and beyond anyone who’s natural due to the steady stream of hormone in your bloodstream versus being inconsistent spikes when natural.

 

[LightningLeg]

@chimpanzee19 I’d be interested to see these studies that show AR downregulation

 

[chimpanzee19]

@LightningLeg I’m going to link you to a blog, however there’s a link included to each study referenced: https://www.taeian.com/androgen-rec..._m8lvYMF7OrM0iOJMl6_45r7CV10GlEMOdNW2VxkJJDpU

 

[looking4gainzz]

@chimpanzee19 the problem is they are misrepresenting the word down regulate. Yes after 6 weeks there is a plateau of sorts for most cycles. However that is because of myostatin and other factors rising in response to the increased anabolic activity. No there aren’t finite receptors so sarms don’t waste receptors that could be used by steroids or other sarms. No they do not downregulate after increased exposure to androgens. If they did they would down regulate to our own natural hormones that cleavevto them. The receptor doesn’t know exogenous from endogenous so we would all be suppressed by end of puberty if that were the case. Yes there are limiting factors like myostatin and some we do not even understand yet, but no we don’t desensitize to androgens like we would hexarelin or other peptides.

 

[chimpanzee19]

@looking4gainzz Saying that they’re misrepresenting the word down regulate is more or less semantics. Yes, myostatin increasing is one reason, however there are numerous ways at which processes transpire in the body to decrease stimuli to the androgen receptor. Take a lot of testosterone with no AI? Estrogen interferes and less AR activity takes place. We could all watch a MPMD video and get hung up on semantics of one process by which myostatin interferes with AR regulation, yet there are so many processes that affect the AR, many like you said, that aren’t understood. Essentially anything that interferes with signaling to the AR is down regulating activity and this is typically going to happen when taking steroids that interfere and throw something into the signaling process that is outside the norm of being natural; i.e. why natural test doesn’t down regulate the AR over time.

 

[looking4gainzz]

@chimpanzee19 it is not semantics. Hexarelin directly causes a desensitization at the gh receptor meaning that compound will not work at any dosage without cessation of the compound entirely. The test to estrogen example you brought up is not applicable. The estrogen fills the androgen receptors because they have a higher binding affinity than the test does. The receptor itself if you took something like proviron would be emptied of shbg and now voila…you have more receptors available abs more growth. The receptor does not downgrade ever. It is other receptors and processes that cause the plateau it is not just semantics in the slightest. They are separate distinct processes and those do not in any way cause the actual desensitization of the androgen receptor. Dorian cruised on 400-500 mg test and 200 mg deca for years and than blasted to multiple grams test but only 800 deca. Why??? BecUse the receptor doesn’t downgrade.

 

[ragemedic]

@looking4gainzz
You are correct. The above who talk down-regulation are spreading fake news. Gear use can increase the bodies myostatin which in turn can cause plateaus but it is not from down-regulation.

 

[chimpanzee19]

@looking4gainzz https://physiology.org/doi/full/10.1152/ajpendo.00362.2001

You keep bringing up hexarelin, that has nothing to do with supporting your claims, and yet here I am firing away to the idiot squad with evidence to support my case. It’s not semantics when you bring up many different points that are all correlated in less signals being received by the androgen receptor, yet seems relevant to bring up hexarelin and a completely unrelated receptor. Ok

 

[Jay]

@chimpanzee19 but your “evidence” is a link to a blog that only cites two credible gov studies. Neither of those two says anything to back up your claim.

 

[Forthewin1123]

@chimpanzee19 250lbs ain’t shit though… it really depends on what.your goals are… if your trying to be a open class body builder …I don’t you can take 150mgs ever. Just a regular guy wanting to be for and healthy 150 or a less is probably perfect… …your not wrong… I only disagrees with your 1 sentence about 140mg a week … lot

 

[chimpanzee19]

@Jay What I posted is extrapolating the idea on long term use. Anyone who says AR down regulation is a myth can only reference short term use studies to try and prove their point showing myostatin levels increasing, so I guess we’re at an impasse. Agree to disagree, and move on.

 

[chimpanzee19]

@Forthewin1123 most here weigh nowhere close to 250lbs and to drop from 260lbs to 250lbs simply from cruising at 120mgs really isn’t that bad imo. I personally prefer to take as few drugs/no drugs when cruising and using 200mgs/wk for me would still require some form of low dose AI use