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Is Aromisin preferred over Arimidex
- Thread starter Harbenger
- Start date
thallandchill
New member
Harbenger" pid='65850' dateline='1566437678:
1.) Aromasin has been show to improve lipids while Arimidex has been shown to negatively affect lipids (though mildly).
2.) With Arimidex, you can have a yo-yo effect with your e2 because of the way it works if you don’t stay ontop of it. With Aromasin, you don’t get this yo-yo or rebounding effect because of the way it works HOWEVER it takes longer to recover from crashed e2 (if you do crash it) with Aromasin than Arimidex because of this.
Those are basically the two main reasons I think people have started to use aromasin more often than Adex. Both are effective.
So, Arimidex and Aromasin work in different ways to manage e2. I’m not going to go into specifics, I’m just going to hit the highlights between the two. You can find a lot more in depth explanation between the two on the internet.
1.) Aromasin has been show to improve lipids while Arimidex has been shown to negatively affect lipids (though mildly).
2.) With Arimidex, you can have a yo-yo effect with your e2 because of the way it works if you don’t stay ontop of it. With Aromasin, you don’t get this yo-yo or rebounding effect because of the way it works HOWEVER it takes longer to recover from crashed e2 (if you do crash it) with Aromasin than Arimidex because of this.
Those are basically the two main reasons I think people have started to use aromasin more often than Adex. Both are effective.
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Harbenger" pid='65850' dateline='1566437678:
Arimidex has a 46hr half life. It’s lower dosed. It’s cheaper. You can buy 1gram of raw arimidex for $15. A dose is anywhere from 0.5 to 1.0mg, however like all AI you need to pay close attention to the half life because as you take it eod it can build up and that’s why I never take AI more often then 2x the half life, in this case once every four days. Arimidex binds to aromatase enzymes blocking the conversion of testosterone to estrogen. Bound arimidex+aromatase is reversible with Arimidex and can lead to estrogen rebound once the two dissociate.
Aromasin is a suicide inbitor which permanently disables aromatase enzyme once it binds with aromasin. This prevents estrogen rebound. The half life is 27hrs. I personally never take more then 25mg per week. I recommend not taking more then once a week because that allows you plenty of time to make sure you estrogen levels don’t crash. Remember there is no rebound with Asin, once your aromatase enzyme is bound to aromasin and eliminated it will take some time to recover your aromatase enzyme, so you should allow yourself plenty of time to make sure you really need an AI. Aromasin I use is the Pfizer 25mg tabs, it’s more expensive, when I was taking it might run me $50/yr
It’s better to let your estrogen remain a little elevated, you’ll keep your strength and libido. If you crash your E2, it’s lights out, you won’t want to get out of bed, you will feel like crap.
Conservative use of AI is the sane approach, don’t just take this stuff because you think it’s part of your cycle. Look at yourself and see if you’re getting puffy, ankles swelling, blood pressure is going up. AI will help to dry you out a little.
For me I mix half and half Testosterone with Masteron and use that. I don’t really need an AI with this combo, the Masteron keeps me dried out and since it doesn’t aromatize there’s no real worries. Most of the guys I personally know that run the same combo as me, will run maybe 6.25mg of Aromasin at the most once a week.
And I should mention I never cycle off, I’m a middle aged man, my balls are shot, no sense in wasting time coming off.
Both Arimidex and Aromasin can work.
Arimidex has a 46hr half life. It’s lower dosed. It’s cheaper. You can buy 1gram of raw arimidex for $15. A dose is anywhere from 0.5 to 1.0mg, however like all AI you need to pay close attention to the half life because as you take it eod it can build up and that’s why I never take AI more often then 2x the half life, in this case once every four days. Arimidex binds to aromatase enzymes blocking the conversion of testosterone to estrogen. Bound arimidex+aromatase is reversible with Arimidex and can lead to estrogen rebound once the two dissociate.
Aromasin is a suicide inbitor which permanently disables aromatase enzyme once it binds with aromasin. This prevents estrogen rebound. The half life is 27hrs. I personally never take more then 25mg per week. I recommend not taking more then once a week because that allows you plenty of time to make sure you estrogen levels don’t crash. Remember there is no rebound with Asin, once your aromatase enzyme is bound to aromasin and eliminated it will take some time to recover your aromatase enzyme, so you should allow yourself plenty of time to make sure you really need an AI. Aromasin I use is the Pfizer 25mg tabs, it’s more expensive, when I was taking it might run me $50/yr
It’s better to let your estrogen remain a little elevated, you’ll keep your strength and libido. If you crash your E2, it’s lights out, you won’t want to get out of bed, you will feel like crap.
Conservative use of AI is the sane approach, don’t just take this stuff because you think it’s part of your cycle. Look at yourself and see if you’re getting puffy, ankles swelling, blood pressure is going up. AI will help to dry you out a little.
For me I mix half and half Testosterone with Masteron and use that. I don’t really need an AI with this combo, the Masteron keeps me dried out and since it doesn’t aromatize there’s no real worries. Most of the guys I personally know that run the same combo as me, will run maybe 6.25mg of Aromasin at the most once a week.
And I should mention I never cycle off, I’m a middle aged man, my balls are shot, no sense in wasting time coming off.
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thallandchill
New member
Dexter" pid='65862' dateline='1566441328:
Thank you for giving the more in depth explanation, haha. I was about to go to sleep when I typed my reply out.
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thallandchill" pid='65896' dateline='1566481425:
You use it when you need it and when you lower your doses or stop you stop using the AI.
There are side effects to using AI. Lipid panels worsening, supposedly decreasing bone density, which I’m not certain about because AAS usually increases bone density and weight lifting we know improves it as well.
One more thing. You don’t want to stay on an AI for life. This is for running higher doses of AAS that aromatize.
You use it when you need it and when you lower your doses or stop you stop using the AI.
There are side effects to using AI. Lipid panels worsening, supposedly decreasing bone density, which I’m not certain about because AAS usually increases bone density and weight lifting we know improves it as well.
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MikeAlstott
Active member
Dexter" pid='65903' dateline='1566484916:
I will say that I just started taking Aromasin on cruise because my E2 hovers around 60 without AI. I already feel a lot better, my sleep is better, my mood is better, my libido is better, etc. I will say that I’m using HCG and I may be a rare case, but I definitely feel that I need some AI on cruise. I tried 6.25 a week and it isn’t enough for me personally. I need at least 12.5 mg a week right now.
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MikeAlstott" pid='65917' dateline='1566492372:
12.5mg once a week is a safe dose, if you feel off you simply stop taking it for a while.
My only suggestion is that you wouldn’t want to have to take an AI every week for the rest of your life. You certainly could, but where’s the long term studies of men for 2,3,4 decades?
This is why I suggest anyone starting on AAS and AI make sure they diet down and get the body fat off first before starting cycle or life long replacement. Save yourself the headache of body fat induced aromatase.
20-35 is a sweet spot for E2 typically.
12.5mg once a week is a safe dose, if you feel off you simply stop taking it for a while.
My only suggestion is that you wouldn’t want to have to take an AI every week for the rest of your life. You certainly could, but where’s the long term studies of men for 2,3,4 decades?
This is why I suggest anyone starting on AAS and AI make sure they diet down and get the body fat off first before starting cycle or life long replacement. Save yourself the headache of body fat induced aromatase.
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MikeAlstott
Active member
Dexter" pid='66050' dateline='1566574705:
Also, haven’t really looked at research on long term AI, but it seems prescribed TRT guys are prescribed Arimidex to take weekly.
The thing is I’m not fat. I’m pretty lean and can see abs. I’m assuming I’m ultra sensitive to AI, but for some reason this cruise I’m aromatizing more even with similar dosing protocol to my last cruise. Last cruise I was 100 Test 550 HCG per week and my E2 was mid 40s. This time I’m 120 Test, 500 HCG and it’s mid 60s without AI. A 20 point increase in E2 makes no sense to me with a 20 mg increase in Test. I’m getting the same Test level as last cruise as well… do you have any idea on why this is happening to me? It’s like my body aromatizes more now?
Also, haven’t really looked at research on long term AI, but it seems prescribed TRT guys are prescribed Arimidex to take weekly.
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thallandchill
New member
MikeAlstott" pid='66055' dateline='1566576954:
I tend to use AI’s sparingly and only when I start to notice sides (increased bp from water retention, bloating, broken dick etc.)
To be honest, if you aren’t have any high estrogen side effects I wouldn’t fuck with an AI. My e2 has been in the low 100’s before and I haven’t noticed any side effects whatsoever. I don’t think theres a magic number so to speak that is perfect for everyone.
I tend to use AI’s sparingly and only when I start to notice sides (increased bp from water retention, bloating, broken dick etc.)
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MikeAlstott
Active member
thallandchill" pid='66056' dateline='1566577203:
I’ve felt this before when I had higher test levels. My ratios must’ve been good, but now since I’ve taken the aromasin I feel better in every way.
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thallandchill
New member
MikeAlstott" pid='66059' dateline='1566578312:
Well if you feel better, than keep doing what you’re doing brotha!
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MikeAlstott
Active member
thallandchill" pid='66063' dateline='1566579081:
Thanks brotha. Do you have any idea on why I would need up to 12.5 mg Asin 2x a week with these dosages to feel good?
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thallandchill
New member
MikeAlstott" pid='66064' dateline='1566579198:
Shitty diet, lack of exercise, weight gain, stress, age etc.
I’m not 100% certain as to why in your particular case, however any of these factors CAN contribute to it.
There’s a number of different reasons why, some external that would affect your sharp increase in e2 levels.
Shitty diet, lack of exercise, weight gain, stress, age etc.
I’m not 100% certain as to why in your particular case, however any of these factors CAN contribute to it.
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For me I only use the AI when my blood pressure is going up and if it’s not time for my every 30 day self phlebotomy of 250mls of blood.
Otherwise I find it a difficult balancing act getting dialed in with an AI.
I will say this, don’t just go by the numbers. Too many people get obsessed with the number instead of how they feel.
I don’t need to run an E2 on myself very often. I know for me 100mg/100mg Test and Masteron are all I need each week to feel strong. I don’t even worry about my E2. If I do see my blood pressure going up I might reach for some aromasin, but honestly I notice I lose strength in the gym every time I play around with that stuff.
My blood pressure is 140/88 right now, it’s starting to creep up, my E2 might be a little elevated, but I feel fantastic, my workouts are going great. That’s all I care about.
With an AI I don’t know how many times I just felt off, I didn’t feel like getting out of bed, I wasn’t going into the gym like a madman, I just felt like I was going through the motions, having to force my workouts.
For me since Masteron doesn’t aromatize and I’m only taking 100mg of Test with that, sometimes 150mg if I want to add some prop to enhance my workouts, I don’t think I’ll every get crazy high E2.
Otherwise I find it a difficult balancing act getting dialed in with an AI.
I will say this, don’t just go by the numbers. Too many people get obsessed with the number instead of how they feel.
I don’t need to run an E2 on myself very often. I know for me 100mg/100mg Test and Masteron are all I need each week to feel strong. I don’t even worry about my E2. If I do see my blood pressure going up I might reach for some aromasin, but honestly I notice I lose strength in the gym every time I play around with that stuff.
My blood pressure is 140/88 right now, it’s starting to creep up, my E2 might be a little elevated, but I feel fantastic, my workouts are going great. That’s all I care about.
With an AI I don’t know how many times I just felt off, I didn’t feel like getting out of bed, I wasn’t going into the gym like a madman, I just felt like I was going through the motions, having to force my workouts.
For me since Masteron doesn’t aromatize and I’m only taking 100mg of Test with that, sometimes 150mg if I want to add some prop to enhance my workouts, I don’t think I’ll every get crazy high E2.
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Harbenger
Member
Thank you all for the information.
I have Adex on hand, just ordered some Aromisin.
I’m alternating pin days, Tue, Thur Test / Wed, Fri Mast at my original 200mg TRT levels with 200mg of Mast P.
Maybe I will get to pass on the AI like @“Dexter” .
In the past I used Mast E with zero issues but I’m trying the Mast P this time.
I have Adex on hand, just ordered some Aromisin.
I’m alternating pin days, Tue, Thur Test / Wed, Fri Mast at my original 200mg TRT levels with 200mg of Mast P.
Maybe I will get to pass on the AI like @“Dexter” .
In the past I used Mast E with zero issues but I’m trying the Mast P this time.
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Thanks for sharing you’re experience with aromasin vs adex.
I’ve been running test and deca, sometimes Masteron and tren a few weeks before hitting the beach.
I was religiously taking aromasin 12.5 daily.
I had some red painful pea sized inflammation of gyno hit me. I took extra aromasin right away. A few hours an the pain dissipated. Inflammation was still there but the higher dosages helped until I got some cabergoline which seemed to clear everything up.
Do you think it would have subsided and gone away had I not taken the caber?
I’ve been running test and deca, sometimes Masteron and tren a few weeks before hitting the beach.
I was religiously taking aromasin 12.5 daily.
I had some red painful pea sized inflammation of gyno hit me. I took extra aromasin right away. A few hours an the pain dissipated. Inflammation was still there but the higher dosages helped until I got some cabergoline which seemed to clear everything up.
Do you think it would have subsided and gone away had I not taken the caber?
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MikeAlstott
Active member
Yoitsjer" pid='66466' dateline='1566831827:
Tren and Deca can cause prolactin based gyno which would make sense as to why everything cleared up after you took Caber. I don’t know if it would have gone away on it’s own… Maybe? But taking Aromasin is dealing with your estrogen and taking Caber is dealing with your prolactin so I am inclined to think that the Aromasin wasn’t really helping your gyno if it was caused by high prolactin.
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FixerUpper
New member
thallandchill" pid='65858' dateline='1566439964:
There isn’t much (or any) research showing that AI’s themselves are directly responsible for the unfavorable effects on lipids. Every study I’ve seen looks at patients who had their estradiol virtually eliminated via high dose AI use. Knowing what we know about the role which estrogens play in lipid metabolism, it seems extremely likely that those effects can be attributed to the fact that these patients have little to no estrogen production.
Even if we were to blame the AI’s for the impact on lipid profiles in these studies, we have to consider the dose as well. All of these studies use doses of aromatase inhibitors that FAR exceed what the majority of AAS users are taking. It seems unlikely that low/reasonable doses would have a significant effect.
Regarding Aromasin having a positive effect on lipids, well, it depends what literature you read. There is also research showing Aromasin to have a negative effect on lipid profiles.
I think it’s important to point out that the effects of aromatase inhibitors on lipid profiles are blown WAY out of proportion across steroid forums.
There isn’t much (or any) research showing that AI’s themselves are directly responsible for the unfavorable effects on lipids. Every study I’ve seen looks at patients who had their estradiol virtually eliminated via high dose AI use. Knowing what we know about the role which estrogens play in lipid metabolism, it seems extremely likely that those effects can be attributed to the fact that these patients have little to no estrogen production.
Even if we were to blame the AI’s for the impact on lipid profiles in these studies, we have to consider the dose as well. All of these studies use doses of aromatase inhibitors that FAR exceed what the majority of AAS users are taking. It seems unlikely that low/reasonable doses would have a significant effect.
Regarding Aromasin having a positive effect on lipids, well, it depends what literature you read. There is also research showing Aromasin to have a negative effect on lipid profiles.
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