Mast VS primo???

[Gullinbursti]

I mean

is it though? You’re right in the fact that there’s zero research that I know of. But the scientific basis of my hypothesis is sound. We know that compounds from the different families have different mechanisms of action and hit different receptors. It’s not far fetched to extrapolate that the same family of compounds hits the same receptors.

But I left the medical field and biochem research decades ago! So someone else will have to dig for that and do that research.

Obviously I’m making a bro science statement. But I do base it with some degree of background knowledge.

Every steroid is different but they all hit the same androgen receptors. Use compounds that work together synergistically but multiple dhts together shouldn't be an issue in the way you're thinking

 

[Maidenless]

I mean

is it though? You’re right in the fact that there’s zero research that I know of. But the scientific basis of my hypothesis is sound. We know that compounds from the different families have different mechanisms of action and hit different receptors. It’s not far fetched to extrapolate that the same family of compounds hits the same receptors.

But I left the medical field and biochem research decades ago! So someone else will have to dig for that and do that research.

Obviously I’m making a bro science statement. But I do base it with some degree of background knowledge.

They all bind to the androgen receptor, that said you only have a limited number of androgen receptors. Once you reach a certain amount of total androgens there are so few available receptors that you aren’t really getting any more androgen driven gene expression from taking more.

But the reason that different compounds have different effects is due to their effects on other receptors. All steroid hormones are structurally very similar, as they all have a cholesterol base, so many aas will have varying effects on estrogen, progesterone, mineralcorticoid, glucocorticoid, etc. receptors. Additionally these receptors have varying structures in different areas of the body, so there is also variation in how any given steroid hormone will affect the receptors in any given part of the body.

If a compound has different effects than another one, it’s because it’s binding to different related receptors in different ways, all across the body. So if there is a compound that has an effect you’d like to benefit from, you can use it regardless of if you’re using another from the same family

 

[Morningcupofjuice]

No. Comparing test to mast, to tren, to nandrolone to primo. Everything with the exception of ment, mtren, exotic compounds like that. Some very reputable sources, coaches, etc are claiming that the only difference between conventional aas, as listed above are the side effects. Meaning tren will be very cosmetic and great strength gains, nand may be "wetter", etc. But the actual muscle gain is extremely close mg per mg and anything else is the illusion because of the cosmetic effects which will dissipate after stopping your cycle anyway. Honestly I believe it. I can see why you wouldn't or others don't but I absolutely do. Maybe tren has a bit more of an edge but not much. It just does other more dramatic things on the side

I can't necessarily get behind this, but I do see where you are coming from. In my personal opinion looking at the drugs you have listed above Tren would be most useful for the growth of lean muscle tissue nandrolone next then primo and mast last (although the cosmetic affect may be the most aesthetic with mast). To each their own I guess.

 

[MalcolmWare16$]

so off topic a bit, but shipment arrived. I had to order bigger syringes to run this cycle. So ordered 3ml lauer lock. What gauge need for drawing and pinning? My current gauges don’t seem to fit right, it was super hard to draw and pin today.

 

[Kartist915]

Been reading through this, I just ordered a Primo, Test, and Mast blast for the end of next month. I haven’t decided on the specific numbers yet, so I’m really glad I found this post. Not only for the dosing advice in it but because OP’s story is my story exactly. Anavar annihilated my liver. I took it after being told that’s it’s processed by the kidneys and that it’s very mild, etc etc. And for most people that may be true, but for me it is completely hepatotoxic and gave me DILI (drug induced liver injury) I’m on a very light cruise right now (test 125 wk, mast 100wk, deca 60 wk) while that recovers. I’m just 3 weeks off of the Var and my numbers are almost back to normal.

My advice to the OP is never ever F*&k with orals again, sounds like your’e like me, and if you are, you can’t listen to the general wisdom concerning liver stuff, they mean well but they’re not like us so their experience is different and that’s what theyre offering.

Also, maybe of some interest to you, the reason I decided on Test Mast Primo for my next blast is that I wanted to do a Holy Trinity blast (test mast Tren) but I’m afraid of Tren for my liver. its the highest risk injectable for hepatotoxicity and I would strongly recommend staying away from it for anyone like you and I who just can’t mess with orals at all Due to liver issues.
I’m new to this forum but not new to gear, when I saw this post I had to join.
thanks for having me

 

[Kartist915]

so off topic a bit, but shipment arrived. I had to order bigger syringes to run this cycle. So ordered 3ml lauer lock. What gauge need for drawing and pinning? My current gauges don’t seem to fit right, it was super hard to draw and pin today.

I buy 3ml 23g syringes and separate 20g tips. I use the tips to draw and then put the original tip back to pin. You can use the 20g a few times too since they’re just for drawing

 

[Kartist915]

so off topic a bit, but shipment arrived. I had to order bigger syringes to run this cycle. So ordered 3ml lauer lock. What gauge need for drawing and pinning? My current gauges don’t seem to fit right, it was super hard to draw and pin today.

Oh, I just realized how old that is, my bad lol

 

[MalcolmWare16$]

Oh, I just realized how old that is, my bad lol

All good . To touch on the tren being liver toxic, I’m not sure that’s a thing, it’s hard on the kidneys but not liver ( from my understanding ). I cycle on and off the holy trinity, currently blasting 250 test c ( makes me break out horribly any higher ) 800 Mast P and 500 Tren A. Feel great.

 

[Kartist915]

All good . To touch on the tren being liver toxic, I’m not sure that’s a thing, it’s hard on the kidneys but not liver ( from my understanding ). I cycle on and off the holy trinity, currently blasting 250 test c ( makes me break out horribly any higher ) 800 Mast P and 500 Tren A. Feel great.

Have you checked your liver function since doing Tren? What were the symptoms when the Anavar started bothering you? For me it was brutal heartburn and acid reflux, like painful to the point of holding my chest and groaning lol. And I started to have these pounding headaches

 

[imagepb]

Been reading through this, I just ordered a Primo, Test, and Mast blast for the end of next month. I haven’t decided on the specific numbers yet, so I’m really glad I found this post. Not only for the dosing advice in it but because OP’s story is my story exactly. Anavar annihilated my liver. I took it after being told that’s it’s processed by the kidneys and that it’s very mild, etc etc. And for most people that may be true, but for me it is completely hepatotoxic and gave me DILI (drug induced liver injury) I’m on a very light cruise right now (test 125 wk, mast 100wk, deca 60 wk) while that recovers. I’m just 3 weeks off of the Var and my numbers are almost back to normal.

My advice to the OP is never ever F*&k with orals again, sounds like your’e like me, and if you are, you can’t listen to the general wisdom concerning liver stuff, they mean well but they’re not like us so their experience is different and that’s what theyre offering.

Also, maybe of some interest to you, the reason I decided on Test Mast Primo for my next blast is that I wanted to do a Holy Trinity blast (test mast Tren) but I’m afraid of Tren for my liver. its the highest risk injectable for hepatotoxicity and I would strongly recommend staying away from it for anyone like you and I who just can’t mess with orals at all Due to liver issues.
I’m new to this forum but not new to gear, when I saw this post I had to join.
thanks for having me

Where’d you get the Var? I’m not your doctor but Var is a highly studied Anabolic. It’s been studied in high doses and for 2+ years of use. It’s been studied in children, old people, aids patients, etc. As a medical professional I’m not naive to the fact that there’s always an outlier with unique symptoms. 9/10 times, in instances like this, the person was receiving another oral other than Var. Var is one of the most highly faked anabolics on the market, right next to primo.

 

[Kartist915]

Where’d you get the Var? I’m not your doctor but Var is a highly studied Anabolic. It’s been studied in high doses and for 2+ years of use. It’s been studied in children, old people, aids patients, etc. As a medical professional I’m not naive to the fact that there’s always an outlier with unique symptoms. 9/10 times, in instances like this, the person was receiving another oral other than Var. Var is one of the most highly faked anabolics on the market, right next to primo.

I got my var from a reputable source, same place i get all my gear. It’s an oral ansbolic steroid. I was taking no other orals. It started a couple weeks after taking it, and stopped immediately upon stopping.. if you are a medical professional, then you know that any oral anabolic steroid has low-medium risk of liver toxicity in the best of cases. You don’t even have to dig very far in Google to find warnings about Anavar and liver damage, this is not some surprising controversial information, its safe for your liver compared to other oral AAS medications, but still risky. And for those prone to it. It’s almost assured, as evidenced by me and the OP. It’s not even really a debate. If it works safely for you thats awesome, I’m only talking to the folks for whom, like me, it is not safe.

 

[imagepb]

I got my var from a reputable source, same place i get all my gear. It’s an oral ansbolic steroid. I was taking no other orals. It started a couple weeks after taking it, and stopped immediately upon stopping.. if you are a medical professional, then you know that any oral anabolic steroid has low-medium risk of liver toxicity in the best of cases. You don’t even have to dig very far in Google to find warnings about Anavar and liver damage, this is not some surprising controversial information, its safe for your liver compared to other oral AAS medications, but still risky. And for those prone to it. It’s almost assured, as evidenced by me and the OP. It’s not even really a debate. If it works safely for you thats awesome, I’m only talking to the folks for whom, like me, it is not safe.

Again, I understand there are outliers. As I’m sure you’re aware, actual Liver Injury presents in less than 1% of patients. Moderately elevated (2-3x) serum levels and Alkaline phosphate levels present in around 45% of patients but often asymptomatic and self limiting! They usually subside promptly once use is discontinued. I’m genuinely curious what kind of Injury did you incur? Usually if injury does occur, the patient has a bland cholestasis. But there are a few other injuries that can occur.

Did you ever have your Var tested? And what dosage were you taking? Any other injectables? How was your drinking history before and during?

 

[Kartist915]

I’d have to break out the paperwork to tell you the specific diagnosis, i am not a medical professional. Heres what the bloodwork looked like, i cant find the paperwork with the diagnosis I just remember DILI. I did not have the anavar tested, I gave the rest to my friend who loves them and does 80mg a day without problem. Hes already finished them. I have not had a sip of alcohol since 2012, I had hep c cured about 5 years ago, and I'm a recovering addict. Which could be the reason it did to me what it did to me. Its not really relevant to this conversation, if you are in the small percentage that, for whatever reason, has trouble with the effects of orals on your liver, then Anavar may not be safe either. I am one of those types of people and I am talking to others like me. Heres the bloodwork images, make of them what you will.

Oh and also an ultrasound was done too. After that they told me it would heal, and that I was lucky I stopped when I did. My labs from 2 days ago are almsot normal. At the time i was on var i was also on 250 mg test e wk, 200mg mast e a week. I am still on both of those now, lower doses though. About 150 and 100 respectively.