Trestolone is the only steroid in production today that is capable of sustaining normal male physiology in the complete absence of testosterone, including sexual functioning. In many users, the compound conveys positive psychological effects including a sense of confidence, euthymia and well-being—effects to some degree shared by DHT-related compounds Testosterone, Dianabol, Proviron and Masteron. However, MENT is not subject to metabolism by the 5α-reductase enzyme, so the compound's psychological benefits are unrelated to the those conveyed by DHT. Unlike sister compound Dimethandrolone (DMAU), MENT undergoes aromatization, so all the benefits of estrogen will still be conveyed on cycle: extra strength, better glycogen use, androgen receptor upregulation, increased GH output, and boosted IGF-1.
c. TRT Dosage
In a 1992 study in rats investigating the pharmacology of MENT, researchers found the anabolic potency of MENT to be 10× greater than Testosterone, while also being 12× more suppressive to the HTPA. The average male produces 4-7mg of testosterone daily to keep muscle mass and sexual function, so 400-700mcg of MENT daily (10× less) is sufficient to produce the same results. A clinical contraceptive study employed doses of one, two and four patches that released 400mcg per day each, for an effective daily dose of 400mcg, 800mcg, and 1600mcg (1.6mg). Clinical studies ranging from 400-700mcg on up to 1-2mg found a close approximation to TRT dose. Given the lack of side effects or negative impact on bloodwork, many bodybuilders have opted to follow an “enhanced” cruise protocol of 5-10mg/day—technically a blast and not a true cruise at all, yet yielding enhanced strength and recovery with minimal impact on measurable markers.
