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PT-141 aka Bremelanotide aka Vyleesi

MikeAlstott

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Has anyone used PT-141 before? I’ve been experimenting with it recently and have been having a great time. It recently became FDA approved as a treatment for hypoactive sexual desire disorder in premenopausal women and is prescribed under “Vyleesi.” It’s essentially Melanotan 2 without the tanning effects, just the sexual effects.

Was wondering what you guys have used dosage wise. The highest I’ve gone so far is 5 mg in one go. Tolerance seems to build with this, but I’ve heard of something like 3 mg EOD for regular desired effects. Some people might only need 1 - 1.5 mg. I believe the prescribed Vyleesi dosage is 1.75 mg.

When paired with 10 mg Cialis it’s hard to control my johnson. I went to go pick up some pizza with my lady the other night and my johnson was on perma-erect, I sat there outside waiting for it to go down and it just wouldn’t. So we devised a plan to go in and pick up the pizza, she would walk in front of me to shield my erection from view. I walked in the door and began to pay for the pizza. The man behind the counter stood in utter disbelief as he stared at my crotchal region. The jig was up. I couldn’t look this man in the eye anymore and I sensed the same from him. We looked loosely in each others direction as we embarrassingly thanked each other and I proceeded to waddle out the door holding the pizza box above my waist so as to cloak the gargoyle.

I might have to try dosing a whole vial at once.
 
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Musclehead34

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@MikeAlstott used it 3 years ago from bluesky. Didn’t give claimed effects . did make my face flush red.
 
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Musclehead34

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@MikeAlstott 500 to 1mg if im right. Not sure if I went to 2mg on final dose. Used up the 10mg vial over 2 month span.

Never used MT2. Might in 2021, do you have any input on MT2 effects. I dont use tan beds, want to preserve my tattoos as long as I can. MT has a lot of bad feedback on cancer causing and dark circles under eyes?
 
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MikeAlstott

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@Musclehead34 Most likely that dosage was too low. 3 mg and up seems to be the sweet spot.

As for MT2, I think you are referring to the effect it has where it can darken preexisting moles. Not sure about the dark circle under eyes as that never happened to me. I usually would pin 300-500 mcg before and after each tanning session and then 300-500 on the days where I wasn’t tanning. You don’t have to use tanning beds, just the regular sun light will do, but I did notice for me the tanning bed was nice a couple times before I got out in the sun. I can’t tan without MT2.

One could argue MT2 helps prevent skin cancer, possibly because I normally burn, but with MT2 I do not burn.
 
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